What is the effect of denaturation on the structure of proteins?
Denaturation of proteins: Proteins are very sensitive to the action of heat, change of pH, presence of electrolytes and radiations (particularly of short wavelength). Whenever proteins are subjected to such changes in the surroundings, they undergo some structural changes leading to disruption of three dimensional structure. This causes permanent loss of activity to proteins. Disruption of the native conformation of protein, by changing its environment, resulting in loss of its biological activity, is known as denaturation of proteins.
Define the following as related to proteins:
(i) Peptide linkage (ii) Primary structure (iii) Denaturation.
