What is the difference between a nucleoside and a nucleotide?
Nucleosides:
1. It contains only two basic components of nucleic acids, i.e., a pentose sugar and a nitrogenous base.
2. During their formation, 1-position of the pyrimi-dine or 9-position of the purine is linked to C, of the sugar (ribose or deoxyribose) by a β-linkage.
Nucleotides:
1. It contains all the three basic components of nucleic acids, i.e., a phosphoric acid group, a pentose sugar and a nitrogenous base.
2. These are formed by esterification of one of the hydroxyl groups (usually C5—OH of the sugar part) of the nucleoside with phosphoric acid.
Define the following as related to proteins:
(i) Peptide linkage (ii) Primary structure (iii) Denaturation.