Explain the considerations in drug designing.
Two considerations of major importance in drug designing are:
(i) Choice of drug target: Drug usually interacts with biological macro-molecules such as carbohydrates, lipids, proteins, and nucleic acid. These biological macro-molecules are called targets.
(ii) Drug Metabolism: A drug travels through the body in order to reach the target. Therefore, its design should be such that it reaches the target without being metabolised in between. Also, after its action, it should be excreted without causing harm to the body.
Describe the following with suitable examples:
(i) Preservative
(ii) Artificial sweeteners
(iii) Antioxidants
(iv) Edible colours.
Describe the following with suitable examples:
(i) Tranquilizers.
(ii) Antifertility drugs.
(iii) Antihistamines.
Detergrent molecules associated with ___________ hydrocarbon tail is a source of pollution.
