The genetic defect-Adenosine Deaminase (ADA) deficiency may be cured permanently by
periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
administering denosine deaminase activators
introducing bone marrow cells producing ADA into cells at early embryonic stages
introducing bone marrow cells producing ADA into cells at early embryonic stages
A.
periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
severe combined immunodeficiency (SCID) caused by adenosine deaminase deficiency (AIDA) is the first genetic disorder to be treated with gene therapy. T-cell-directed gene transfer was useful in the treatment of ADA-SCID, whereas the retroviral-mediated gene transfer to haematopoietic stem cells was insufficient for the achievement of clinical benefits.
In which of the following haemocyanin pigment is found?
Lower invertebrates
Echinodermata
Insecta
Annelida
An organic substance bound to an enzyme and essential for its activity is called
coenzyme
holoenzyme
apoenzyme
apoenzyme
Carbohydrates are commonly found as starch in plant storage organs. which of the following five properties of starch (A-E) make it useful as a storage material?
A) Easily translocated
B) Chemically non-reactive
C) Easily digested by animals
D) Osmotically inactive
E) Synthesized during photosynthesis
The useful properties are
(B) and (C)
(B) and (D)
(A), (C) adn (E)
(A), (C) adn (E)
One gene-one enzyme relationship was established for the first time in
Neurospora crassa
Salmonella typhimurium
Escherichia coli
Escherichia coli
Match the storage products listed under column I with the organism given under column II, choose the appropriate option from the given options
Column I | Column II | ||
A | Glycogen | 1 | Sargassum |
B | Pyrenoids | 2 | Nostoc |
C | Laminarin and mannitol | 3 | Polysiphonia |
D | Floridean starch | 4 | Spirogyra |
5 | Agaricus |
A | B | C | D |
3 | 4 | 1 | 5 |
A | B | C | D |
4 | 3 | 5 | 2 |
A | B | C | D |
5 | 4 | 1 | 3 |
A | B | C | D |
2 | 1 | 4 | 3 |
All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is
lactate dehydrogenase
isocitrate dehydrogenase
malate dehydrogenase
malate dehydrogenase
Fixation of one CO2 molecule through the Calvin cycle requires.
1 ATP and 2NADPH2
2 ATP and 2NADPH2
3 ATP and 2NADH2
2 ATP and 1 NADPH2
The figure given below shows the conversion of a substrate to product by an enzyme. In which one of the four option (a-d), the components of reaction labelled as A, B, C and D are identified correctly?
A |
B |
C |
D |
Potential energy |
Transition state |
Activation energy with enzyme |
Activation energy without enzyme |
A |
B |
C |
D |
Transition energy |
Potential energy |
Activation energy with enzyme |
Activation energy with out enzyme |
A |
B |
C |
D |
Potential energy |
Transition energy |
Activation energy with out enzyme |
Activation energy with enzyme |
A |
B |
C |
D |
Potential energy |
Transition energy |
Activation energy with out enzyme |
Activation energy with enzyme |
What is the role of NAD+ in cellular respiration?
It functions as an enzyme.
It functions as an electron carrier.
It is the final electron acceptor for anaerobic respiration.
It is a nucleotide source for ATP synthesis.