Which of the following disorders are caused due to recessive autosomal mutations?
Turner"s syndrome and sickle cell anaemia
Edward's syndrome and Down's syndrome
Cystic fibrosis and phenylketonuria
Alzheimer's disease and Huntington's chorea
C.
Cystic fibrosis and phenylketonuria
Gene related human disorders are determined by mutations in single gene. The pattern of inheritance of Mendelian disorders can be traced in a family by Pedigree analysis.
Cystic Fibrosis is an abnormal recessive disorder of infants, children and young adults. It occurs due to an abnormal recessive autosomal allele present on chromosome 7. Presence of fibrous cysts in pancreas. It produces a defective glycoprotein that causes formation of thick mucus in skin, lungs, pancreas and other secretory organs.
Phenylketonuria is an inborn, autosomal, recessive metabolic disorder in which homozygous recessive individual lacks the enzyme phenylalanine hydroxylase needed to change phenylalanine to tyrosine in liver. Lack of this enzyme is due to the abnormal autosomal recessive gene on chromosome 12.
Assertion : Insulin is antagonistic to glucagon.
Reason : It is an anabolic hormone.
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
Assertion : Auditory ossicles are small bones present in the cavity of inner ear.
Reason : Auditory ossicles maintain the balance of air pressure between two sides of ear drum.
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false
If both assertion and reason are false.
Assertion : Pharyngeal nephridia play a role in the conservation of water in the earthworm.
Reason : They help the earthworm in keeping the skin moist for cutaneous respiration.
If both assertion and reason are true and reason is the correct explanation of assertion
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
Assertion : Pantothenic acid deficiency is probably the most common vitamin deficiency.
Reason : Macrocytic anaemia is a characteristic feature of pantothenic acid deficiency.
If both assertion and reason are true and reason is the correct explanation of assertion
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false
Which one is correct?
Salmonella typhi and Haemophilus influenzae cause pneumonia
Widal test is done for malaria
Entamoeba histolytica causes amoebiasis
Wuchereria causes enterobiasis
Which of the following is correct regarding genetic code?
UUU is the initiation codon which also codes for phenylalanine.
There are 64 triplet codons and only 20 amino acids
Three random nitrogen bases specify the placement of one amino acid
UAA is the nonsense codon which also codes for methionine