What is the difference between a nucleoside and a nucleotide?

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130.

What is the difference between a nucleoside and a nucleotide?


Nucleosides:

1. It contains only two basic components of nucleic acids, i.e., a pentose sugar and a nitrogenous base.

2. During their formation, 1-position of the pyrimi-dine or 9-position of the purine is linked to C, of the sugar (ribose or deoxyribose) by a β-linkage.



Nucleotides:

1. It contains all the three basic components of nucleic acids, i.e., a phosphoric acid group, a pentose sugar and a nitrogenous base.

2. These are formed by esterification of one of the hydroxyl groups (usually C5—OH of the sugar part) of the nucleoside with phosphoric acid.

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