Short Answer Type
One Word AnswersShort Answer TypeWhich forces are involved in holding the drugs to the active site of enzyme.
Ionic bonding, hydrogen bonding, van dar Waals interactions or dipole-dipole interaction are involved in holding the drugs to the active site of enzymes and receptors.
For example, if amino acid serine is present nearby the substrate held on active site, then its -OH group is free to act as a nucleophile in the enzyme catalysed reaction.
Amino acid serine, aspartic acid and phenylalanine are present on the active site of an enzyme. Explain which forces may be involved in bonding the drug to the enzyme if the drug inhibits the holding of the substrate on the active site of the enzyme.
Long Answer TypeWith the help of examples, explain how do following type of drugs functions?
(i) Analgesics
(ii) Antacids
(iii) Antifertility drugs
Short Answer TypeLow level of noradrenaline is the cause of depression. What type of drugs are needed to cure this problem? Name two drugs.
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