Which of the cyclins have/ has essential functions in S phase of

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 Multiple Choice QuestionsMultiple Choice Questions

1.

Which of the following is not possible in biological systems?

  • DNA → RNA → Protein

  • Protein → RNA → DNA

  • Glucose → Amino acid → Proetin

  • RNA → DNA → Protein


2.

Which cyclin is involved in formation of pre-transcriptional enhancer binding protein (PTEB)?

  • Cyclin D

  • Cyclin K

  • Cyclin E

  • Cyclin T


3.

Puromycin blocks translation. Mode of action of drug puromycin is

  • binds to A site and stop elongation

  • Stops peptidyl transferase activity

  • Binds EF-Tu-GTP and prevent initiation

  • Do not allow termination of translation


4.

Somatic hypermutation in immunoglobulin genes is responsible for

  • Class witching

  • Affinity maturation

  • Clonal selection

  • VDJ recombination


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5.

Interaction of antibody with antigen is like lock and key. The major force responsible for antigen antibody interaction is

  • Hydrogen bond

  • Van der wall interaction

  • Disulphide bond

  • Peptide bond


6.

Which is common cytokine secreted by both TH1 and TH2 cells?

  • IL-2

  • IL-4

  • INF-γ

  • IL-5


7.

Major Histocompatibility complex - I (MHC-I) is present at

  • All nucleated cells

  • Only on antigen presenting cells

  • Only on B and T lymphocytes

  • Macrophages and dendritic cells


8.

Major reason for evolution for diversity in immune system is

  • natural selection

  • Neutral mutation

  • Directed evolution

  • Co-evolution


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9.

Which of the cyclins have/ has essential functions in S phase of cell cycle?

  • A type

  • B type

  • D type

  • Both B and D type


A.

A type

There are two main groups of cyclins: G1/S cyclins – essential for the control of the cell cycle at the G1/S transition, Cyclin A / CDK2 – active in S phase. Cyclin D / CDK4, Cyclin D / CDK6, and Cyclin E / CDK2 – regulates transition from G1 to S phase.


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10.

During generation of an action potential, depolarization is due to

  • K+ efflux

  • Na+ efflux

  • Na+ influx

  • K+ influx


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