Prestin, a membrane protein, is found in which one of the followi

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 Multiple Choice QuestionsMultiple Choice Questions

151.

The rank/ abundance plot given below illustrates three well-known species abundance curves (a, b, c)

Based on the shapes of the curves select the correct option.

  • a - exponential; b - log normal; c - geometric series.

  • a - broken stick; b - geometric series; c - log normal

  • a - broken stick;b - log normal; c - geometric series.

  • a - exponential; b - geometric series; c - log normal


152.

In an intact cell patch-clamp experiment,

  • two electrodes are inserted into the cytosol but at different depths.

  • one electrode is applied to the plasma membrane in a region containing only lipids and one into the cytosol.

  • two electrodes are applied to the plasma membrane, one in a region containing only lipids and the other in a region containing one or few ion channels.

  • one electrode is applied to the plasma membrane containing one or few ion channels and one electrode inserted into the cytosol.


153.

Given below are organelles (column A) and properties associated with the organelles (column B).
Column A Column B
A. Lysosomes i. Anterograde transport from ER to Golgi
B. cis-Golgi ii. CLathrin - coated vesicles
C. trans- Golgi iii. Cop I vesicle budding.
D. Cop II vesicles iv. Mannose-6-phosphate receptor
E. Endocytic vesicles v. Protein aggregate for secretion.

Choose the option that matches the organelles with the most appropriate property.

  • A - iv; B - iii; C - v; D - i; E - ii

  • A - v; B - iv; C - i; D - v; E - ii

  • A - iii; B - v; C - i; D - iv; E - ii

  • A - iv; B - v; C - ii; D - i; E - iii


154.

Cell cycle checkpoints are surveillance mechanisms that ensure order and fidelity of events of the cell cycle. Given below are some of the checkpoint proteins and their functions.
A. Mad2 i. Prevention of Cdc 14 activation.
B. Tem 1 ii. Prevention of Cdc20 activation.
C. ATM, ATR iii. Inhibition of p21CIP
  iv. Inhibition of separase action

Match the checkpoint protein with its function.

  • A - iv; B - i and ii C - iii

  • A - ii and iv; B - i; C - iii

  • A - ii; B - i and iii; C - iv

  • A - ii and iv; B - iii; C - i


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155.

Fertilization in sea urchin involves interaction of sperm Bindin with its receptor EBR1, a 350 kDa glycoprotein on the egg vitelline membrane. The plot given below shows the status of membrane potential and levels of EBR1, Na+ and K+ in an unfertilized egg.

Which one of the following graphs best represents the condition within an egg 1-3 seconds after fertilization?


156.

Several types of molecules including the transmembrane glycoproteins can function as matrix receptors and co-receptors. However, the principal receptors on animal cells for binding most extracellular matrix proteins are the integrins. Which of the following statements is NOT true for integrins?

  • Integrins are transmembrane linker proteins that link to the cytoskeleton.

  • An integrin molecule is composed of two non-covalently associated glycoprotein subunits α and β. Both subunits span the cell membrane, with short intracellular C-terminal tails and large N-terminal extracellular domains.

  • the extracellular portion of the integrin dimer binds to specific carbohydrate residues in extracellular matrix proteins.

  • The intracellular portion binds to a complex of proteins that form a linkage to the cytoskeleton.


157.

Which one of the following statements related to components/features of senescence in plants is INCORRECT?

  • Programmed cell death in plants may generate functional cells or tissues.

  • Senescence can be induced by application of cytokinins and delayed by overexpression of salicylic acid

  • Plants defective in autophagy demonstrate accelerated plant senescence

  • Leaf senescence is regulated by NAC and WRKY genes families.


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158.

Prestin, a membrane protein, is found in which one of the following cells of the organ of Corti? 

  • Inner hair cells

  • Inner phalangeal cells

  • Outer hair cells

  • Outer phalangeal cells


C.

Outer hair cells

Prestin is a protein, evolved from a family of anion transporters, that is only present in the outer hair cells of mammals. In response to changes in membrane potential, prestin changes conformation within the plasma membrane between long and short forms. Because prestin serves, by itself, as a motor, electromotility is fast—orders of magnitude faster than skeletal muscle contraction. This means that the outer hair cell shortens and lengthens in response to sinusoidal deflection of the hair bundle at physiological frequencies. The shortening and lengthening of the outer hair cell pulls the basilar  membrane up and down, thereby amplifying the excursion of the basilar membrane within the organ of Corti. (Fig.) Thus, outer hair cells boost the stimulus that reachethe inner hair cells.

                                     


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159.

Which one of the listed below is a P-type ion transporter?

  • Mg2+ and fe2+

  • Mg2+ and fe3+

  • Mg2+ and Cl-

  • Na+, -K+, Ca2+ and H+


160.

Match the enzymes is Column A with their respective biological functions in column B:
 Column A  Column B
(a) Lipases (i) Catalysis of ATP-dependent translocation of the aminopholipids, phosphatidylethamine and phosphatidy-lserine from the plasma membrane
(b) Flippases (ii) Catalysis of ATP-dependent translocation of plasma membrane phospholipids from the cytosolic to the extracellular leaflet.
(c) Floppases (iii) Catalyze hydrolysis of triacylgycerols.
(d) Scramblases (iv) Catalyze the movement of any membrane phospholipid across the bilayer down its concentration gradient.

Choose the correct combination of answers from the given options given below:

  •  

      (a) (b) (c) (d)
    A (iii) (i) (ii) (iv)
  •   (a) (b) (c) (d)
    B (i) (iii) (iv) (ii)
  •   (a) (b) (c) (d)
    C (iv) (ii) (i) (iii)
  •   (a) (b) (c) (d)
    D (ii) (iv) (iii) (i)

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