1.

A wild form animal gives one egg and mutant from gives three egg per year respectively. If all parents and progenies survive, then what would be the ration of number of wild to mutant after four years?

• 4

• 2 × 4

• 2 × 3 × 4

• 2⁴

A physiological disorder X always leads to the disorder Y. However, disorder Y may occur by itself. A population shows 4% incidence of disorder Y. Which of the following inferences is valid?

• 4% of the population suffers from both X and Y

• Less than 4% of the population suffers from X

• At least 4% of the population suffers from X

• There is no incidence of X in the given population

The distance between gene A and B is 10cM. If a genotype is selfed, the percentage of progeny with genotype aabb will be:

• 10%

• 25%

• 0.25%

• 0.01%

The following is the biochemical pathway for purple pigment production in flowers of sweet pea:

$\mathrm{Colorless} \mathrm{Precursor}1 \stackrel{\mathrm{Allele} \mathrm{A}}{\to } \mathrm{colorless} \mathrm{precursor} 2\stackrel{\mathrm{Allele} \mathrm{B}}{\to } \mathrm{Purple} \mathrm{pigments}$

Recessive mutation of either gene A or B leads to the formation of white flowers. A cross is made between two parents with the genotype: AaBb x aabb. Considering that the two genes are not linked, the phenotypes of the expected progenies are

• 9 purple: 7white

• 3 white: 1purple

• 1 purple: 1white

• 9 purple: 6light puple: 1 white

The frequencies of alleles ‘A’ and ‘a’ in a population at Hardy‐Weinberg equilibrium are 0.7 and 0.3 respectively. In a random sample of 250 individuals taken from the pupation, how many are expected to be heterozygous?

• 112

• 81

• 105

• 145

In a heterozygous two recessive mutation at different site will give mutant phenotype when genes involved are

• Allelic and placed in cis

• Allelic and placed in trans

• Non-allelic and placed in cis

• Non-allelic and plced in trans

The µ and σ of with length (a normally distributed parameter) in a population of fruit flies are 4 and 0.2 mm respectively. In a random sample of 400 fruit files, how many individuals are expected to have wing lengths greater than 4.4 mm?

• 20

• 64

• 10

• 336

Aneuploid females with only one X chromosome is a characteristic of individuals with

• Cri du chat syndrome

• Klinefetler syndrome

• Down syndrome

• Truner syndrome

Binding of erythropoietin to its EPO receptor leads to activation of signaling pathway termed as:

• JAK-STAT pathway   

• NF-kβ pathway   

• Apaf-smad pathway  

• Tyrosine kinase pathway   

An insertion of single nucleotide in coding region of gene leads to frame shift mutation and result is formation of non-functional protein. Under certain condition second suppressor mutation in another gene may result into formation of functional protein. How suppressor mutation can do this

• There is insertional mutation in gene of t-RNA anticodon such that it is able to interact with four nucleotide codon.            

• Mutation in gene of ribosome leading to frame shift over transcript  

• Mutation in gene whose product bulge out extra nucleotide     

• Another mutation reverses the original insertion