The genetic defect-Adenosine Deaminase (ADA) deficiency may be c

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 Multiple Choice QuestionsMultiple Choice Questions

21.

The figure given below shows the conversion of a substrate to product by an enzyme. In which one of the four option (a-d), the components of reaction labelled as A, B, C and D are identified correctly?

  • A

    B

    C

    D

    Potential energy

    Transition state

    Activation energy with enzyme

    Activation energy without enzyme

  • A

    B

    C

    D

    Transition energy

    Potential energy

    Activation energy with enzyme

    Activation energy with out enzyme

  • A

    B

    C

    D

    Potential energy

    Transition energy

    Activation energy with out enzyme

    Activation energy with enzyme

  • A

    B

    C

    D

    Potential energy

    Transition energy

    Activation energy with out enzyme

    Activation energy with enzyme

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22.

The genetic defect-Adenosine Deaminase (ADA) deficiency may be cured permanently by

  • periodic infusion of genetically engineered lymphocytes having functional ADA cDNA

  • administering denosine deaminase activators

  • introducing bone marrow cells producing ADA into cells at early embryonic stages

  • introducing bone marrow cells producing ADA into cells at early embryonic stages


A.

periodic infusion of genetically engineered lymphocytes having functional ADA cDNA

severe combined immunodeficiency (SCID) caused by adenosine deaminase deficiency (AIDA) is the first genetic disorder to be treated with gene therapy. T-cell-directed gene transfer was useful in the treatment of ADA-SCID, whereas the retroviral-mediated gene transfer to haematopoietic stem cells was insufficient for the achievement of clinical benefits.

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23.

Carbohydrates are commonly found as starch in plant storage organs. which of the following five properties of starch (A-E) make it useful as a storage material?

A) Easily translocated

B) Chemically non-reactive

C) Easily digested by animals

D) Osmotically inactive

E) Synthesized during photosynthesis

The useful properties are 

  • (B) and (C)

  • (B) and (D)

  • (A), (C) adn (E)

  • (A), (C) adn (E)

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24.

One gene-one enzyme relationship was established for the first time in

  • Neurospora crassa

  • Salmonella typhimurium

  • Escherichia coli

  • Escherichia coli

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25.

All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is

  • lactate dehydrogenase

  • isocitrate dehydrogenase

  • malate dehydrogenase

  • malate dehydrogenase

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26.

An organic substance bound to an enzyme and essential for its activity is called

  • coenzyme

  • holoenzyme

  • apoenzyme

  • apoenzyme

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27.

What is the role of NAD+ in cellular respiration?

  • It functions as an enzyme.

  • It functions as an electron carrier.

  • It is the final electron acceptor for anaerobic respiration.

  • It is a nucleotide source for ATP synthesis.


28.

Fixation of one CO2 molecule through the Calvin cycle requires.

  • 1 ATP and 2NADPH2

  • 2 ATP and 2NADPH2

  • 3 ATP and 2NADH2

  • 2 ATP and 1 NADPH2


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29.

Match the storage products listed under column I with the organism given under column II, choose the appropriate option from the given options
Column I Column II
A Glycogen 1 Sargassum
B Pyrenoids 2 Nostoc
C Laminarin and mannitol 3 Polysiphonia
D Floridean starch 4 Spirogyra
    5 Agaricus

  • A B C D
    3 4 1 5
  • A B C D
    4 3 5 2
  • A B C D
    5 4 1 3
  • A B C D
    2 1 4 3

30.

In which of the following haemocyanin pigment is found?

  •  Lower invertebrates

  • Echinodermata

  • Insecta

  • Annelida


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