An example of competitive inhibition of an enzyme is the inhibition of:
succinic dehydrogenase by malonic acid
cytochrome oxidase by cyanide
hexokinase by glucose-6-phosphate
carbonic anhydrase by carbon dioxide
Antibiotic flavicin is obtained from
Aspergillus flavus
Aspergillus clavatum
Streptomyces grieseus
Streptomyces fradiae
Antifeedant property occurs in
nicotine
azadiractin
rotenone
cinerin
B.
azadiractin
Antifeedants are organic compound produced by plants to inhibit attack by insects and grazing animals. These chemical compounds are typically classified as secondary metabolites in that they are not essential for the metabolism of the plant, but instead confer longevity. Antifeedants exhibit a wide range of activities and chemical structures as biopesticides.
Azadirachtin are extract of neem tree, it has several effects on phytophagous insects and is thought to disrupt insect molting by antagonizing the effects of ecdysteroids. This effect is independent of feeding inhibition, which is another observed effect of the compound.1,10 The antifeedant/repellent effects are dramatic, with many insects avoiding treated crops, although other chemicals in the seed extract, such as salanin, have been shown to be responsible for these effects.
Carbohydrates, ingested in the diet, are hydrolyzed by the enzyme :
pepsin
cellulose
- amylase
glycosidase
Quaternary structure of protein
consists of four subunits
may be either or
is unrelated to two functions of the protein
is dictated by the primary structures of the individual subunits