Study the following Columns.

Column I	Column II
A. Hydrogen bond	1. Adenine - Deoxyribose
B. N - glycosidic linkage	2. Glucose - Fructose
C. Phosphodiester bond	3. Leucine - Glycine
D. Peptide bond	4. Nucleotide - Nucleotide in polynucleotide chain 5. Guanine cytosine on opposite strands of DNA.

The correct match is

• A - 5; B - 1; C - 4; D - 3

• A - 2; B - 1; C - 5; D - 3

• A - 5; B - 3; C - 4; D - 2

• A - 1; B - 4; C - 5; D - 2

Select the correct statements out of the four (I-IV) given below about lac operon.

I. Glucose or galactose may bind with the repressor and inactivate it.

II. In the absence of lactose, the repressor binds with the operator region.

III. The Z-gene codes for permease.

IV. This was elucidated by Francois Jacob and Jacques Monad.

The correct statements are

• II and III

• I and III

• II and IV

• I and II

Match the following column I with column II

Column I (Genes)	Column II (Types)
A. Genes for glycolysis	1. Pseudogenes
B. Genes for nitrate reductase	2. Multigenes
C. Globin gene family	3. House keeping genes
D. mRNA gene	4. Inducible genes

• A - 4; B - 3; C - 1; D - 2

• A - 3; B - 4; C - 2; D - 1

• A - 1; B - 2; C - 4; D - 3

• A - 2; B - 1; C - 3; D - 4

214.

Consider the following statements about DNA replication.

I. A replisome is the largest functional unit in DNA replication factories.

II. RNA polymerase complexes are responsible for transcribing the newly synthesised RNAs into their mature form.

III. DNA polymerases add new deoxyribonucleotides to the 3' end of a DNA strand.

IV. A replication bubble is a region of single stranded DNA that arises due to unwinding of DNA in same direction by primase

Choose the incorrect statement(s)

• I and II

• III and IV

• I, II and IV

• I, II, III and IV

Which of the following statement is not true about Griffith's experiment?

• The experiment was conducted in 1928

• The experiment occurs with Streptococcus pneumoniae

• R and S-strain of bacteria

• The experiment proves the process of transduction

In protein synthesis the base sequence of mRNA determines the primary structure of polypeptide chain because

• it determine the sequence of alignment of amino acid charged tRNA molecule

• there is one to one coding relationship between each base on mRNA and amino acid

• each amino acid is defined by a pair of base on mRNA

• amino acid molecule align directly on the polynucleotide on mRNA

What do you mean to the mutation in which replacement of a nucleotide occur by another similar type?

• Inversion

• Transition substitution

• Transversion substitution

• Insertion frame- shift

Part of gene which codes for an enzyme is

• cistron

• codon

• exon

• intron

Which of the following codons does not select any amino acid?

• UAG

• UAA

• UGA

• All of these

Operator genes are controls to which gene mechanism?

• Structural gene

• Activator gene

• Regulator gene

• Modulac gene