Multiple Choice Questions

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The main reason why antibiotics could not solve all the problems of bacteria mediated diseases is

  • insensitivity of the individual following prolonged exposure to antibiotics

  • inactivation of antibiotics by bacterial enzymes

  •  decreased efficiency of the immune system

  •  the development of mutant strains resistant to antibiotics.


D.

 the development of mutant strains resistant to antibiotics.

A major problem in the treatment of bacterial mediated diseases is that many bacteria have been found to show resistance to antibiotics. The emergence of antibiotic-resistant bacteria is closely linked to the extent that antibiotics are used in humans and items of human diet. Resistant strains may appear rapidly or slowly, according to the amount or type of antibiotic used. Bacteria occur in such large numbers that there is a high chance of a mutant individual eventually appearing in the population. As soon as it does, use of the antibiotic to which it is resistant will give it a selective advantage over non-resistant types and it will multiply and eventually become the dominant type.

Antibiotics may also be destroyed by enzymes inside the cells being targetted. A well-known and important example is the group of enzymes known as penicillinases which hydrolyses and destroys penicillins and cephalosporins.


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Assertion: Hybridoma cells are shifted to a medium deficient in nutrient which cannot be synthesized by myeloma cells.

Reason: This medium allows selection of hybridoma cells.

  • If both assertion and reason are true and reason is the correct explanation of assertion

  • If both assertion and reason are true but reason is not the correct explanation of assertion

  • If assertion is true but reason is false

  • If both assertion and reason are false.


Assertion : Antigen can be easily recognized because it has antigenic determinants.

Reason : The recognition ability is innate.

  • If both assertion and reason are true and reason is the correct explanation of assertion

  • If both assertion and reason are true but reason is not the correct explanation of assertion

  • If assertion is true but reason is false

  • If both assertion and reason are false


Which of the following match is correct?

  • Emphysema : reduction of surface area of alveoli and bronchi

  • Pneumonia : occupational disease with asbestos

  • Silicosis : inflammation of alveoli

  • Asthma : excessive secretion of bronchial mucus


Which one of the following is an environment related disorder with the correct main cause

  • Black lung disease (pneumoconiosis) found mainly in workers in stone quarries and crushers.

  • Blue baby disease (methaemoglobinaemia) due to heavy use of nitrogenous fertilizers in the area.

  • Non-hodgkin's lymphoma found mainly in workers involved in manufacture of neem based pesticides.

  • Skin cancer mainly in people exposed to benzene and methane.


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When children play bare footed in pools of ditty water and flood water, they may suffer from disease like

  • leptospirosis and bilharzia

  • malaria, amoebic dysentery and leptospirosis

  • bilharzia, infective hepatitis and diarrhoea

  • guinea worm infection, elephantiasis and amoebic dysentery.


Which of the following sets includes all bacterial disease

  • Cholera, typhoid, mumps

  • Tetanus, tuberculosis, measles

  • Malaria, mumps, poliomyelitis

  • Diphtheria, leprosy, plague


The binding of antibodies to the antigens to produce a large insoluble complex is known as

  • antibody-antigen complex

  • agglutination

  • immunisation

  • suppressor cell reaction.


Which one of the following is the correct statement regarding the particular psychotropic drug specified

  • Morphine leads to delusions and disturbed emotions.

  • Barbiturates cause relaxation and temporary euphoria.

  • Hashish causes alteration of thoughts, perceptions and hallucinations.

  • Opium stimulates nervous system and causes hallucinations.


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When a man inhales air containing normal concentration of O2 as well as CO he suffers from suffocation because

  • CO reacts with O2 reducing its percentage in air

  • haemoglobin combines with CO instead of O2 and forms carboxyhaemoglobin

  • CO affects diaphragm and intercostal muscle

  • CO affects the nerves of the lungs.


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