Multiple Choice Questions

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During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure, what is it’s DNA-binding sequence?

  • TTAA

  • AATT

  • CACC

  • CACC


D.

CACC

TATA box is present in eukaryotic promotor region. It has a resemblance with pribnow box of prokaryotes. TATA box was identified by Dr. Hogness and so, it is called as Hogness box. It is a 7 bp long region located 20 bp upstream to the start point. During the process of transcription the RNA polymerase (a holoenzyme which has a core unit and sigma factor for proper initiation of transcription) binds to TATA box due to which DNA assumes a saddle-like structure at this place.

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Molecular basis of organ differentiation dpends on the modulation in transcription by

  • RNA polymerase

  • ribosome

  • transcription factor

  • transcription factor

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What is antissense technology? 

  • A cell displaying a foreign antigen used for synthesis of antigens

  • Production of somaclonal variants in tissue cultures. 

  • When a piece of RNA that is complementary to sequence is used to stop expression of a specific gene.

  • When a piece of RNA that is complementary to sequence is used to stop expression of a specific gene.

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The linking of antibiotic resistance gene with the plasmid vector became possible with

  • DNA ligase

  • endonucleases

  • DNA polymerase

  • DNA polymerase

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Telomere repetitive DNA sequences control the function of eukaryotic chromosomes because they

  • act as replicons.

  • are RNA transcription initiator

  • help chromosome pairing

  • help chromosome pairing

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Cry-I endotoxins obtained from Bacillus thringiensis are effective against 

  • mosquitoes

  • flies

  • nematodes

  • nematodes

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The Okazaki fragments in DNA chain growth

  • result in transcription

  • polymerize in the 3’ - to - 5’ direction and forms replication fork

  • prove semi-conservative natuire of DNA replication

  • prove semi-conservative natuire of DNA replication

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Differentiation of organs and tissues in a developing organism, is associated with

  • developmental mutations

  • differential expression of genes

  • lethal mutations

  • lethal mutations

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The two polynucleotide chains in DNA are

  • parallel

  • discontinuous

  • antiparallel

  • antiparallel

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Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?

  • Thymine, Uracil - Pyrimidines

  • Uracil, Cytosine - Pyrimidines

  • Guanine, Adenine - Purines

  • Guanine, Adenine - Purines

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