Multiple Choice Questions

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Which of the following represents Klinefelter's syndrome?

  • XX

  • XO

  • XY

  • XXY


D.

XXY

Klinefelter's syndrome is a chromosomal abnormality due to which an individual has two X-chromosomes and one Y-chromosome ie, XXY. Such persons are sterile male and may exhibit secondary female characters. They also have underdeveloped genitalia, sparse body hair and exhibit some degree of breast development. They possess 47 chromosomes instead of normal 46 chromosomes. The interphase nuclei of their cells possess one barr body.


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A person with the sex chromosomes XXY suffers from :

  • Down's syndrome

  • Turner's syndrome

  • Gynandromorphism

  • Klinefelter's syndrome


Down's syndrome occurs as a result of

  • trisomy

  • tetrasomy

  • autopolyploidy

  • allopolyploidy


One of the following is sex-influenced character

  • Appearance of beard

  • Baldness in male

  • Docile behaviour of female

  • Low BMR in female


The map distance between the genes A and B is 3 units, between B and C is 10 units and between C and A is 7 units. The order of the genes in a linkage map constructed on the above data would perhaps be

  • A, B, C 

  • A, C, B

  • B, C, A

  • B, A, C


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9: 3: 3: 1 ratio is modified to 9 : 7 ratio due to

  • complementary gene

  • epistatic gene

  • hypostatic gene

  • supplementary gene


The absence of which clotting factor leads to haemophilia-A?

  • Factor VII

  • Factor VIII

  • Factor IX

  • Factor X


Which of the following conditions is related to haemophilia?

  • A responsible recessive gene present in the X-chromosome

  • A responsible dominant gene presentin the X-chromosome

  • A responsible dominant gene present in the Y-chromosome

  • A responsible dominant gene present in the autosomal chromosome


Which one of the following conditions in chromosome number is called monosomy?

  • 2n + 1

  • 2n + 2

  • 2n - 1

  • 2n - 2


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Indicate, the inheritance of which of the following is controlled by multiple alleles?

  • Colourblindness

  • Sickle cell anaemia

  • Blood group

  • Phenylketoneuria


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