Multiple Choice Questions

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When adenoma is converted to metastatic adenocarcinoma, which of the following combination of proteins is almost certainly to be degraded?

  • Type IV collagen and lamanin

  • Fibronectin and β2 integrin

  • Metalloprotease and serine protease

  • Elastin and selectin


A.

Type IV collagen and lamanin

When adenoma is converted to metastatic adenocarcinoma, type IV collagen and laminin are degraded.


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The part of the embryo from which the ectoderm, mesoderm, and endoderm are formed in chick is known as

  • primitive streak

  • hypoblast

  • epiblast

  • cytotrophoblast


Which of the following is considered to be a combined B- and T-cell deficiency?

  • Ataxia-telangiectasia

  • Swiss type agammaglobulinemia

  • Wiskott-Aldrich syndrome

  • Bruton's agammaglobulinemia


Bacteriophage T4 infects E. coli and injects its DNA inside the cell. The transcription of viral genes occurs in three stages: immediate-early, early, and late. All the promoters on the viral genome are available, but the control takes place at the level of

  • promoter strength

  • modification of host RNA polymerase

  • synthesis of new polymerases

  • turn over rate of RNA synthesis


Which of the following is NOT associated with insulin action?

  • Increased glucose transport

  • Increased glycogen formation

  • Enhanced lipolysis in adipose tissue

  • Decreased rate of gluconeogenesis


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The homologue of β-catenin in Drosophila is 

  • Fushi tarazu

  • Engrailed

  • Armadillo

  • Cubitus interruptus


Which protein secreted by the amphibian induces neural tissue formation by inhibiting Bone Morphogenetic Protein?

  • β-catenin

  • Noggin

  • Dickkopf

  • Dishevelled


Gram-negative bacteria, Klebsiella pneumoniae, upon infecting humans, results in severe septic shock after a few hours of infection. Which of the following is not true for this type of infection?

  • Cell wall endotoxins cause overproduction of cytokines

  • Septic shock can be treated by anti-TNFα antibodies.

  • Recombinant bacterial proteins can be used for the treatment of septic shock.

  • Recombinant TNFα receptor antagonists can be used for the treatment of septic shock.


Which of the floral whorls is affected in apetala 3/ pistillata (ap3/ pi) mutants?

  • Sepals and Petals

  • Petals and stamens

  • Stamens and carpels

  • Sepals and stamens


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The cap-binding protein (eIF4E), which is involved in the global regulation of translation, is highly regulated in eukaryotic cells. In an experiment, a researcher transfected mammalian cells with (eIF4E) gene for its overexpression. Due to this, the cells will undergo

  • apoptosis

  • neoplastic transformation

  • No change

  • differentiation