State significance of primary and secondary structures of protei

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135. State significance of primary and secondary structures of proteins.


The sequence in which the amino acids are arranged in a protein is called the primary structure of protein. The primary structure of protein determines its function and is critical to its biological activity. The change of just one amino acid in the sequence can alter its biological activity.

Secondary structure of proteins refers to the arrangement of polypeptide chains which arises as a result of hydrogen bonding. It arises due to regular folding of the back bone of polypeptide chain. It is two types.
(a) α-helix-Globular protein have α-helix structure.
(b) β-pleated-fibrous proteins have α-pleated structure.

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136.

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137.

What are nucleic acids? Explain their functions in the synthesis of proteins.

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139.

State differences between α-helix and β-pleated sheet structure.

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140.

State differences between primary and secondary structure of a protein.

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