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Coordination Compounds

Long Answer Type

191.

What is meant by stability of coordinate compound in solution? State the factors which govern stability of complexes.

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Short Answer Type

192. What is meant by the chelate effect? Give an example.

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193. Discuss briefly the role of coordination compounds in biological systems.

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194. Discuss briefly the role of coordination compounds in analytical chemistry.

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195. Discuss briefly the role of coordination compounds in medicinal chemistry.

Medicinal Chemistry: Many complex compounds are used in medicines. Some common examples are:

(i) Vitamin B₁₂ used to prevent anaemia is a complex compound of cobalt.

(ii) The complex of calcium and EDTA is used in the treatment of lead poisoning. Inside the body calcium in the complex is replaced by lead. The more soluble lead – EDTA complex is eliminated in urine.

(iii) The platinum complex cis-[Pt(NH₃)₂Cl₂] known as cis platin is used in the treatment of cancer.

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