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 Multiple Choice QuestionsMultiple Choice Questions

51.

Width of the DNA molecule is

  • 15 Ao

  • 20 Ao

  • 25 Ao

  • 34 Ao


52.

The protein α-1 antitrypsin is used to treat which of the following disease?

  • Cancer

  • Rhematoid arthritis

  • Emphysema

  • ADA deficiency disease in children


53.

The dominant epistasis ratio is

  • 9:3: 3:1

  • 12:3:1

  • 9:3:4

  • 9:6:1


54.

Bacillus thuringiensis (Bt) strains have been used for designing novel

  • Bio metallurgical technique

  • Bio mineralization process

  • Bio Insecticidal Plants

  • Bio Fertilizers


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55.

Bacillus thuringiensis (Bt) strains have been used for designing novel

  • bio metallurgical technique

  • bio mineralization process

  • bio insecticidal plants

  •  bio fertilizers


56.

In recombinant DNA technique, the term vector refers to

  • Donor DNA, is identified and picked up through electrophoresis

  • Plasmid transfers DNA into living cell

  • Collection of the entire genome in form of plasmid

  • Enzyme, cuts the DNA at specific sites


57.

Which one of the following is a reorganization site for restriction enzymeBam HI?

  • 5ʹ– GAATTC – 3ʹ 3ʹ – CTTAAG – 5ʹ

  • 5ʹ – GGATCC – 3ʹ 5ʹ – CCATGG – 3ʹ

  • 5ʹ – GGATCC -– 3ʹ 3ʹ – CCTAGG – 5ʹ

  • 5ʹ– GAATTC – 3ʹ 5ʹ– GTTAAC – 3


58.

Which one of the following pair is not correct?

  • Mangolian idiocy – 21st chromosome

  • Patau syndrome – 13th chromosome

  • Cri-Du-Chat – 11th chromosome

  • Edward syndrome – 18th chromosome


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59.

Which one of the following pair is not correct?

  • Single-stranded DNA

  • Single-stranded RNA

  • Double-stranded DNA

  • None of the above


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60.

Consider these sentences regarding to the structure and nature of DNA.

(I) DNA has tow pyrimidine bases which contain single ring structure.

(II) In DNA, the composition of bases should be A +TG +C = 1

(III) Each base pair of DNA is 3.4Å apart from the base pair.

(IV) The nucleosome model DNA packaging was proposed by Kornberg and Thomas.

  • I and III

  • I, II and III

  • II, III and IV

  • I, III and IV


D.

I, III and IV

Erwin Chargaff (1950) made quantitative analysis of DNA and showed that the composition of DNA molecules varies in complex ways depending upon the source of DNA. He proposed Base Equivalence rule or Chargaff's rule, which states that for double-stranded DNA, the proportion of adenine always equals to that of thymine and proportion of guanine always equals to that of cytosine.
i.e. A=T and G=C.

It follows that, an equal proportion of purines and pyrimidines is always seen in a double-stranded DNA
i.e.

A + G = T + C or A +GT + C = 1


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