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 Multiple Choice QuestionsMultiple Choice Questions

141.

Which of the following is true for a recessive disease in Family A and B?

  • In family A, both the parents are homozygous recessive

  • In family B, both the parents are heterozygous dominant.

  • In family B, both the parents are heterozygous recessive

  • In family A, both the parents are heterozygous recessive.


142.

Assertion: In a pedigree analysis, <5> represents five unaffected offsprings.

Reason: In a pedigree analysis, the offsprings are numbered with arabic numerals (1, 2, 3 .....) and a generation is numbered with roman numerals (I, II, III...).

  • If both assertion and reason are true and reason is the correct explanation of assertion.

  • If both assertion and reason are true but reason is not the correct explanation of assertion.

  • If assertion is true but reason is false.

  • If both assertion and reason are false.


143.

Assertion: Hbs Hbs denotes the homozygous condition for sickle-cell anaemia.

Reason: It occurs due to substitution of glutamic acid by valine at the 6 position of (B-chain of Hb.

  • If both assertion and reason are true and reason is the correct explanation of assertion.

  • If both assertion and reason are true but reason is not the correct explanation of assertion.

  • If assertion is true but reason is false.

  • If both assertion and reason are false.


144.

Assertion : Only a boy child could be born with a substitution of glutamic acid by valine on 6 codon of beta-chain of haemoglobin.

Reason : The gene for the above mutation is found on Y-chromosome.

  • If both assertion and reason are true and reason is the correct explanation of assertion.

  • If both assertion and reason are hue but reason is not the correct explanation of assertion.

  • If assertion is true but reason is false.

  • If both assertion and reason are false.


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145.

Which of the following disorders are caused due to recessive autosomal mutations?

  • Turner"s syndrome and sickle cell anaemia

  • Edward's syndrome and Down's syndrome

  • Cystic fibrosis and phenylketonuria

  • Alzheimer's disease and Huntington's chorea


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146.

Which of the following diseases is also called Christmas disease?

  • Sickle-cell anaemia

  • Haemoglobinuria

  • Myocardial infarction

  • Haemophilia- B


D.

Haemophilia- B

Haemophilia B is due to deficiency of factor IX. Also known as Christmas factor. The patient may experience prolonged bleeding following any injury or wound, and in severe cases there is spontaneous bleeding into muscles and joints.

Sickle cell anemia is an inherited form of anemia. It is a condition in which there are not enough healthy red blood cells to carry adequate oxygen throughout your body.

Haemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine.

Myocardial infarction or heart attack occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.


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147.

Assertion : Antirrhinum is a good example to understand incomplete dominance.

Reason : Heterozygotes show characteristics of both the alleles.

  • If both assertion and reason are true and reason is the correct explanation of assertion

  • If both assertion and reason are true but reason is not the correct explanation of assertion

  • If assertion is true but reason is false

  • If both assertion and reason are false.


148.

Which of the following is correct

  • Henking discovered the small Y-chromosome.

  • Drosophila also shows XX-XY sex determination like human.

  • Birds have ZZ-ZW sex determination, where females are ZZ & males are ZW.

  • Grasshoppers show XX-XY sex determination


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149.

Percentage of recombination between A and B is 9%, A and C is 17%, B and C is 26% , then the arrangement of genes is

  • ABC

  • ACB

  • BCA

  • BAC


150.

Which of the following conditions represents a case of co-dominant genes?

  • A gene expresses itself, suppressing the phenotypic effect of its alleles

  • Genes that are similar in phenotypic effect when present separately, but when together interact to produce a different trait

  • Alleles, both of which interact to produce a trait, which may or may not resemble either of the parental types

  • Alleles, each of which produces an independent effect in a heterozygous condition


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