The cap-binding protein (eIF4E), which is involved in the global regulation of translation, is highly regulated in eukaryotic cells. In an experiment, a researcher transfected mammalian cells with (eIF4E) gene for its overexpression. Due to this, the cells will undergo

• apoptosis

• neoplastic transformation

• No change

• differentiation

32.

Bacteriophage T4 infects E. coli and injects its DNA inside the cell. The transcription of viral genes occurs in three stages: immediate-early, early, and late. All the promoters on the viral genome are available, but the control takes place at the level of

• promoter strength

• modification of host RNA polymerase

• synthesis of new polymerases

• turn over rate of RNA synthesis

Gram-negative bacteria, Klebsiella pneumoniae, upon infecting humans, results in severe septic shock after a few hours of infection. Which of the following is not true for this type of infection?

• Cell wall endotoxins cause overproduction of cytokines

• Septic shock can be treated by anti-TNFα antibodies.

• Recombinant bacterial proteins can be used for the treatment of septic shock.

• Recombinant TNFα receptor antagonists can be used for the treatment of septic shock.

Which of the following is NOT associated with insulin action?

• Increased glucose transport

• Increased glycogen formation

• Enhanced lipolysis in adipose tissue

• Decreased rate of gluconeogenesis

When adenoma is converted to metastatic adenocarcinoma, which of the following combination of proteins is almost certainly to be degraded?

• Type IV collagen and lamanin

• Fibronectin and β₂ integrin

• Metalloprotease and serine protease

• Elastin and selectin

Which of the following is considered to be a combined B- and T-cell deficiency?

• Ataxia-telangiectasia

• Swiss type agammaglobulinemia

• Wiskott-Aldrich syndrome

• Bruton's agammaglobulinemia

The part of the embryo from which the ectoderm, mesoderm, and endoderm are formed in chick is known as

• primitive streak

• hypoblast

• epiblast

• cytotrophoblast

Which protein secreted by the amphibian induces neural tissue formation by inhibiting Bone Morphogenetic Protein?

• β-catenin

• Noggin

• Dickkopf

• Dishevelled

The homologue of β-catenin in Drosophila is 

• Fushi tarazu

• Engrailed

• Armadillo

• Cubitus interruptus

Which of the floral whorls is affected in apetala 3/ pistillata (ap3/ pi) mutants?

• Sepals and Petals

• Petals and stamens

• Stamens and carpels

• Sepals and stamens