The cap-binding protein (eIF4E), which is involved in the global regulation of translation, is highly regulated in eukaryotic cells. In an experiment, a researcher transfected mammalian cells with (eIF4E) gene for its overexpression. Due to this, the cells will undergo
apoptosis
neoplastic transformation
No change
differentiation
Bacteriophage T4 infects E. coli and injects its DNA inside the cell. The transcription of viral genes occurs in three stages: immediate-early, early, and late. All the promoters on the viral genome are available, but the control takes place at the level of
promoter strength
modification of host RNA polymerase
synthesis of new polymerases
turn over rate of RNA synthesis
Gram-negative bacteria, Klebsiella pneumoniae, upon infecting humans, results in severe septic shock after a few hours of infection. Which of the following is not true for this type of infection?
Cell wall endotoxins cause overproduction of cytokines
Septic shock can be treated by anti-TNFα antibodies.
Recombinant bacterial proteins can be used for the treatment of septic shock.
Recombinant TNFα receptor antagonists can be used for the treatment of septic shock.
Which of the following is NOT associated with insulin action?
Increased glucose transport
Increased glycogen formation
Enhanced lipolysis in adipose tissue
Decreased rate of gluconeogenesis
When adenoma is converted to metastatic adenocarcinoma, which of the following combination of proteins is almost certainly to be degraded?
Type IV collagen and lamanin
Fibronectin and β2 integrin
Metalloprotease and serine protease
Elastin and selectin
Which of the following is considered to be a combined B- and T-cell deficiency?
Ataxia-telangiectasia
Swiss type agammaglobulinemia
Wiskott-Aldrich syndrome
Bruton's agammaglobulinemia
The part of the embryo from which the ectoderm, mesoderm, and endoderm are formed in chick is known as
primitive streak
hypoblast
epiblast
cytotrophoblast
Which protein secreted by the amphibian induces neural tissue formation by inhibiting Bone Morphogenetic Protein?
β-catenin
Noggin
Dickkopf
Dishevelled
The homologue of β-catenin in Drosophila is
Fushi tarazu
Engrailed
Armadillo
Cubitus interruptus
C.
Armadillo
The homologue of β-catenin in Drosophila is Armadillo. It plays an important role in wingless signaling and in the assembly of adherens junctions.
Which of the floral whorls is affected in apetala 3/ pistillata (ap3/ pi) mutants?
Sepals and Petals
Petals and stamens
Stamens and carpels
Sepals and stamens