Multiple Choice QuestionsThe oligopeptide, F-A-R-P-M-T-S-R-P-G-F, is treated with trypsin, chymotrypsin, and carboxypeptidase-B. Apart from the original peptide, the number of fragments obtained will be:
4
3
2
0
Which one of the following interaction plays a major role in stabilizing B-DNA?
Hydrogen bond
Hydrophobic interaction
Van der Waal’s interaction
Ionic interactions
Phosphatidylserine, an important component of biological membrane, is located in
The outer leaflet but flipflops to the inner leaflet under specific conditions.
Both the leaflets.
The middle of the bilayer
The inner leaflet but flipflops to outer leaflet under specific conditions.
Major disadvantage of using liposome as a targeted drug delivery vehicle is that
It gets internalized by phagocytosis inside lysosomes.
It is very unstable and has low shelf-life.
It gets intercalated in cell membranes.
Its drug entrapment efficiency is very low.
A major stimulus for spore formation in bacteria is
nutrition limitation
heat stress
cold stress
pH stress
ATP-binding cassette (ABC) transporters
Are all P-glycoproteins.
Are found only in eukaryotes.
Are both: a membrane-spanning domain that recognizes the substrate and an ATP-binding domain.
Affect translocation by forming channels.
All cytosolic proteins have nuclear export signals that allow them to be removed from the nucleus when it reassembles after
Meiosis
Mitosis
Both mitosis and meiosis
DNA replication
Site-specific recombination results in precise DNA rearrangements, which is limited to specific sequences. The enzymes that are important out the process are
Restriction endonuclease and DNA polymerase
Nuclease and ligase
DNA polymerase and ligase
DNA polymerase and DNA gyrase.
Which of the following statements is NOT true about small interfering RNA (siRNA)?
siRNA has a 21-25 nucleotide sequence with 2 nucleotides overhanging at the 3’end.
siRNA is processed by the RNA protein complex RISC.
siRNA is often induced by viruses.
siRNA does not generally act at the level of transcription.
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