31.

Telomerase, an RNA-protein complex that completed the replication of telomeres during DNA synthesis, is specialized

• RNA dependent DNA polymerase

• DNA dependent DNA polymerase

• DNA dependent RNA polymerase

• RNA dependent RNA polymerase

Consider a short double-stranded linear DNA molecule of 10 complete turns with 10.5 bp/turn. The ends of the DNA molecule are sealed together to make a relaxed circle. This relaxed circle will have a linking number of

• 105

• 20.5

• 10.0

• 10.5

In the above signalling cascade, which one of the following molecules is denoted by 'B'?

• STAT 5

• SMAD 6

• GSK3β

• SMAD 4

The secondary antibodies routinely used for the detection of primary antibodies in western blotting experiment are

• anti-allotypic

• anti-idiotypic

• anti-isotypic

• anti-paratypic

Which of the following events will NOT usually lead to the transformation of a normal cell into a cancer cell?

• Gain of function of oncogenes.

• Loss of function of tumor suppressors.

• Gain of function of genes involved in nucleotide excision repair.

• Loss of function of pro-apoptosis related genes.

Which one of the following is a foodborne toxin?

• Tetanus toxin

• Botulinum toxin

• Cholera toxin

• Diptheria toxin

Which one of the following statements is WRONG?

• The megasporocyte develops within the megasporangium of the ovule.

• Megasporocyte undergoes meiosis to produce four haploid megaspores.

• All the four megaspores undergo several mitotic divisions to form female gametophyte in most angiosperms.

• Female gametophyte is haploid.

Certain proteins or mRNAs that are regionally localized within the unfertilized egg and regulate development are called

• gene regualtors

• morphometric determinants

• cytoplasmic determinants

• mosaic forming factors

Cell to cell communication is important in the development of an organism. The ability of a cell to respond to a specific inductive signal is called

• Regional specificity of induction

• Competence

• Juxtacrine signalling

• Instructive interaction

Apical ectodermal ridge induction is essential for tetrapod limb development. Which one of the following is NOT essential for the formation of a functional limb?

• Tbx genes and Wnt

• Androsterone

• Apoptotic genes

• Fibroblast growth factor